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1940年初，伪满医院医生常青是位进步爱国医生，一直利用职务之便为抗联秘密提供药品，安全起见，一直瞒着丈夫。当常青与丈夫年定邦欲离开伪满去关内生活之时，意外得知日军有大批军火秘密入华。常青决定留下阻止，这让不知实情的丈夫很是不解与焦虑。丈夫年定邦曾是国民党力主抗日派。事实让他认清了国民党真剿共消极抗日实质。一次行动中诈死隐居，隐居生活中与常青相恋结合。此时的浩风也被国民党特务找到并以常青的安危作筹码，逼其参与阻止日军秘运军火。夫妻俩为了国家的安危和对方的安全，互相隐瞒着身份并产生了很多误解。在这次行动中，年定邦被抗联战士大无畏的精神所打动。在战火的洗礼中，两人最终坦诚相待、携手完成任务。急救医学博导江晓琪美国学成归来，逛街时遭遇抢劫，没想到抢她的少年劫匪突然昏倒在地。江晓琪立刻送他至XX医院急诊。在分诊台，她遇到了正在指挥为受伤的农民工进行截肢手术的急诊科最具学术权威的主任医师何建一，两人出于中美不同的急救观念争执起来。也就在这一天，一名精神分裂者在急诊室门外持刀闹事导致了一名医生惨死，难脱干系的何建一悲痛万分。江晓琪来到急诊室工作，很快凭着高超医术和对患者人性的关怀在医院上下赢得了很多年轻同事的崇拜。一直觊觎急救科主任位置的副主任刘慧敏，本来以为最大的竞争对手是何建一，不想天降江晓琪，内心对江晓琪的做派各种不满，何建一却对江晓琪抱着审视的目光。江晓琪和何建一在工作中，看到对方的善良、能力和医术，也看到了自己的不足，两个人不断被对方改变着并渐生情愫。"That maybe, half way still want to kill? Finally, on the way back to drag, Liu Gui took a group of people to search the room one by one and found a notebook, as if it were Shan Guoxi's, with the list of people who killed the old summer on it."When the two mountains were fighting, I have fought many battles, However, the most impressive one was the battle to defend position 149 during the July 12 War. I thought that the war was between people and people. I didn't expect to fight with animals here, not only animals, but also flying in the sky and drilling in the soil. If it weren't for the use of new shells to support us later, the position would have been lost. "说起往事，屈明不觉有些神伤。一九三零年广州，赌业蓬勃，当地土豪洪彪、洪豹父子野心并吞全市赌场，幸得「南眼神」罗四海（谢贤）镇压捣乱，洪父子怀恨在心。谭小棠（汪明荃）是当地著名花旦，弟谭升（任达华）出千被四海所擒，小棠为救弟与四海谈判，期后更发展了一段感人的爱情故事。洪彪陷害四海不遂，聘北方千王卓一夫（杨群）与四海斗法，两人打成平手。洪彪唯有另立阴谋，改以收买南北千王于旗下。在一次鸦片买卖中，南北千王被洪彪利用，幸得小棠相救。惜两人最终逃不过洪彪的种种阴谋，四海被害致双目失明，一夫则被挑断手筋。为报血海深仇，两人决集千术之精华授予谭升……